Nucleic Acid Synthesis
Medchemexpress LLC 2'-O-Methylcytidine | 2140-72-9 | MFCD00030635 | 99.7% | 257.25 | 500 MG
2'-O-Methylcytidine is an orally active 2'-substituted nucleoside that acts as an inhibitor of HCV replication with antiviral activity. It inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro, competitively with substrate nucleoside triphosphate. The product is for research use only and not sold to patients.
- Orally active 2'-substituted nucleoside.
- HCV replication inhibitor.
- Possesses antiviral activity.
- Inhibits RNA-dependent RNA polymerase (NS5B)-catalyzed RNA synthesis in vitro.
- Competitive inhibitor with substrate nucleoside triphosphate.
Medchemexpress LLC Trifluridine/tipiracil hydrochloride mixture | 733030-01-8 | 100.0% | 435.76 | 25 MG
Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a potent and orally active nucleoside antitumor agent. It is composed of a 1:0.5 mixture (on a molar basis) of alpha,alpha,alpha-tri-fluorothymidine (FTD) and thymidine phosphorylase inhibitor (TPI). The antitumor activity of TAS-102 primarily stems from its inhibition of thymidylate synthase (TS) and its incorporation into DNA.
- Prevents body weight loss in colorectal and gastric cancer mouse models.
- Reduces relative tumor volume in colorectal and gastric cancer mouse models.
Sigma Aldrich Fine Chemicals Biosciences L-Glutathione oxidized disodium salt >=98%, powder | 103239-24-3 | MFCD00148894 | 500MG
L-Glutathione oxidized disodium salt >=98%, powder | Purity: >=98% | Mol Wt: 656.59 | 103239-24-3 | MFCD00148894 | 500MG
Sigma Aldrich Fine Chemicals Biosciences Guanosine 5'-triphosphate sodium salt hydrate >=90% (HPLC) | 36051-31-7 | MFCD00149227 | 100MG
Guanosine 5'-triphosphate sodium salt hydrate >=90% (HPLC) | Purity: >=90% (HPLC) | 36051-31-7 | MFCD00149227 | 100MG
Medchemexpress LLC P62-mediated mitopha 25mg | 1809031-84-2 | 392.15 g/mol | C14H9IN4O2 | 25 MG
P62-mediated mitophagy inducer is a small-molecule research compound that selectively activates p62-dependent mitophagy without recruiting Parkin or collapsing mitochondrial membrane potential. It is intended for in vitro and cellular research applications and is not for human or clinical use.
- Activates p62-dependent mitophagy in cellular models.
- Does not recruit Parkin or disrupt mitochondrial membrane potential.
- Solid powder, light yellow to yellow, suitable for laboratory handling.
- High purity (99.54%) for biochemical and cellular assays.
- Stable when stored under recommended conditions (powder: -20°C).
Cayman Chemical 11-deoxy ProstaglndIn F1 5mg
11-deoxy PGF1β is a synthetic analog of PGF1β. In contrast to PGF2α and PGF1α, 11-deoxy PGF1β exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 UG/kg.{2217}
Selleck Chemical LLC Fialuridine-E1709-5MG
Fialuridine(FIAU DRG-0098 NSC 678514) is a nucleoside analog with antiviral activity It blocks DNAsynthesis in human cytomegalovirus and hepatitis B as well as herpes simplex